Flexible
One-Pot processing is an extremely
flexible technology. Whether for standard wet granulation, melt granulation,
pelletizing or effervescent production, combined with vacuum or microwave
drying, a one pot processor can achieve the required result. The swinging bowl
option enhances this flexibility even further by its capability to process
older formulations to a high quality standard. With easy and efficient
cleaning, using a CIP system, quick product changeover is achievable.
Compact
Overall investment cost for a certain
technology including installation cost and required cGMP space is becoming more
and more important in the pharmaceutical industry. cGMP production area is
expensive and is minimised wherever possible. One-Pot technology is a very
compact
technology achieved by incorporating several processing steps into
one machine. This reduces the capital cost of the equipment as well as the cGMP
& technical space required for granule
production and therefore the
overall project cost.
Contained
Because of
its very nature, a one pot process is a contained process. No transfers are
required between process steps, except for loading the raw materials and
unloading the dry granules. This is not only beneficial for protecting the
operators from potent products, but also for protecting the
products from
external influences such as heat, light or moisture. Specific solutions are
available for product loading and discharging to achieve the desired level of
containment for the whole process.