Product Know-How - Single Pot processing expertise

Whether the customer's requirement is for mixing, granulation or drying, GEA Pharma Systems has a solution for every processing challenge. The Collette™ Single Pot (or One-Pot) technology offers a choice of mixing, granulation and drying options integrated into one processing vessel. With our help, this allows the customer to choose the most appropriate technique for the product.

With the high-shear granulation technology as the basis, Single Pot processing relies on the
application of a vacuum within the bowl to dry the wet mass. This technique allows drying of pharmaceutical compounds at low temperature, and for minimal environmental exhaust through a very efficient solvent recovery, even if organic solvents are used for granulation.

The vacuum drying process can be enhanced by the addition of a small amount of gas, passing through the product during the drying phase. The gas-assisted vacuum drying (Transflo™) technique results in shorter drying times and lower residual moisture content of the final product.

To further enhance the drying process, microwaves can be added as an additional energy source. Because of the additional energy added to the process, microwave drying is the fastest drying technique available in Single Pot processing. Through careful control of product temperature and forwarded and reflected microwave power, this technique is ideal for fast processing of pharmaceutical products.